Discover where to stay in Berlin through a curated selection of boutique and design hotels located in the city’s most creative and culturally significant neighborhoods, from Mitte to Charlottenburg and Kreuzberg. This guide highlights stylish, well-located accommodations known for their architecture, atmosphere, and proximity to museums, galleries, and major cultural landmarks. Ideal for design-minded travelers and culture lovers, these carefully selected Berlin hotels combine distinctive interiors, historic character, and contemporary comfort for a refined and culturally rich stay in the German capital.

Wilmina (Charlottenburg)

Wilmina is a boutique hotel in Berlin’s Charlottenburg district, set within a former 19th-century women’s prison and courthouse. Originally built in 1896, the complex has been carefully transformed by Grüntuch Ernst Architects, who preserved features such as exposed brick walls and vaulted ceilings while introducing light-filled spaces and refined contemporary design. The result is a peaceful urban sanctuary that balances historical depth with understated modern comfort.

The hotel offers 44 individually designed rooms and suites, ranging from cozy accommodations to spacious penthouses with floor-to-ceiling windows and private terraces. Each room features luxurious COCO-MAT beds made from natural materials, ensuring a restful stay. Guests can enjoy amenities such as a rooftop terrace, a library with a fireplace lounge, a spa with a sauna, and a fitness center. The on-site restaurant, Lovis, led by chef Sophia Rudolph, serves contemporary German cuisine in a setting that opens to a lush garden courtyard.

Wilmina is ideal for a refined stay in Charlottenburg, close to galleries, museums, and Berlin’s leading cultural institutions in the western part of the city.

25hours Hotel Bikini Berlin (Charlottenburg / City West)

25hours Hotel Bikini Berlin is located in the iconic Bikinihaus in the heart of Berlin’s City West district—a mid-century modernist building from the 1950s, nicknamed for its open-sided second floor that gave it the appearance of a two-piece “bikini.” Originally designed by architects Paul Schwebes and Hans Schoszberger, the structure has become a local landmark. The hotel was transformed by designer Werner Aisslinger, who embraced an “Urban Jungle” concept—blending raw industrial elements with lush greenery to mirror the hotel’s unique setting between the bustling city and the adjacent Berlin Zoo.

The hotel features 149 individually styled rooms, divided into Urban and Jungle categories. Urban rooms offer panoramic views of Berlin’s skyline with exposed concrete, steel fixtures, and minimalist design. Jungle rooms overlook the Berlin Zoo and are outfitted with hammocks, warm wood tones, and nature-inspired elements for a calming retreat. The rooftop restaurant NENI Berlin serves a fusion of Mediterranean, Persian, and Austrian cuisine, while the lively Monkey Bar is known for its creative cocktails and sweeping views across the city.

25hours Hotel Bikini Berlin is ideal for a stylish stay in City West, steps away from the concept shopping mall Bikini Berlin and next to the Berlin Zoo, with easy access to Tiergarten, museums, and major cultural landmarks.

Hotel Château Royal Berlin (Mitte)

Hotel Château Royal Berlin is a luxury boutique hotel located on Neustädtische Kirchstraße in Berlin’s city center. The property comprises two restored 19th-century buildings. The hotel’s design was led by David Chipperfield Architects, with interiors by Irina Kromayer. It features herringbone parquet floors, custom oak furnishings, and a rotating collection of over 100 original artworks.

The hotel offers 93 rooms and suites, each individually designed with custom-made furniture, colorful natural stones, and handcrafted ceramic tiles. Some rooms also include freestanding bathtubs or private balconies. Dining options include the signature restaurant Dóttir, a cocktail bar, a winter garden, and a rooftop terrace. A cozy salon with a fireplace is also available to guests.

Hotel Château Royal Berlin is ideal for a refined stay in Mitte, within walking distance of Unter den Linden, Museum Island, and Berlin’s major cultural landmarks.

Telegraphenamt (Mitte)

Hotel Telegraphenamt is a boutique hotel in Berlin’s Mitte district, housed in the city’s former main telegraph office, designed by architects Wilhelm Walter and Max Lehmann and completed in 1916. In 2022, the building was transformed by the award-winning architecture and design firm DREIMETA, which preserved original elements such as historic columns, vaulted ceilings, and exposed brick walls while introducing refined contemporary interiors.

The hotel features 97 uniquely designed rooms, maisonettes, and suites ranging from 21 to 140 square meters. Guests can enjoy seasonal, globally inspired cuisine at ROOT, the hotel’s signature restaurant situated under an impressive glass dome. A wellness center with a sauna and hammam provides a calm retreat from the city’s energy. Adding to the hotel’s vibrant atmosphere is Dieselhaus, a modern brewery-style restaurant located within the same complex. Dieselhaus offers a blend of Bavarian beer culture and Berlin flair, serving traditional German dishes like Schweinebraten and Käsespätzle, complemented by beers from the historic Hofbräuhaus Traunstein.

Telegraphenamt is ideal for a refined stay in Mitte, within walking distance of Museum Island, Hackescher Markt, and Berlin’s key cultural landmarks.

Michelberger Hotel (Friedrichshain)

Michelberger Hotel is a creative boutique hotel located in Berlin’s Friedrichshain district, set in a former 1903 factory building. Original industrial features—including tall ceilings, large factory windows, and exposed brick walls—have been retained and integrated into the hotel’s unique design. The interiors were shaped by a collaboration between designers Werner Aisslinger, Jonathan Tuckey Design, and Sigurd Larsen, combining vintage furniture, custom wallpapers, and playful contemporary details.

The hotel offers 132 uniquely designed rooms, ranging from compact “Cosy” options for solo travelers or couples to expansive “Hideouts” featuring mezzanine sleeping areas, kitchenettes, and private saunas. Each room emphasizes comfort, with high-quality mattresses and organic linens. Guests can enjoy the hotel’s restaurant, which focuses on organic, locally sourced cuisine, a relaxed café-bar serving drinks and snacks, and a lively courtyard that regularly hosts music and social events.

Michelberger Hotel is ideal for a stylish stay in Friedrichshain, close to the East Side Gallery, cultural venues, and central Berlin’s major attractions.

With the interactive map below, you can compare all available accommodation options in the city and find the best prices from a variety of leading providers.

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